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However, there are exceptions to the above for some transgender and intersex men.

*Manus in Indo-European mythology was the first man, see Mannus, Manu (Hinduism).For males during puberty, testosterone, along with gonadotropins released by the pituitary gland, stimulates spermatogenesis, along with the full sexual distinction of a human male from a human female, while women are acted upon by estrogens and progesterones to produce their sexual distinction from the human male.Sometimes gender scholars will use the phrase "hegemonic masculinity" to distinguish the most dominant form of masculinity from other variants. The term man is usually reserved for an adult male, with the term boy being the usual term for a male child or adolescent.However, the term man is also sometimes used to identify a male human, regardless of age, as in phrases such as "men's basketball".If a sperm cell carrying an X chromosome fertilizes the egg, the offspring will typically be female (XX); if a sperm cell carrying a Y chromosome fertilizes the egg, the offspring will typically be male (XY).

Persons whose anatomy or chromosomal makeup differ from this pattern are referred to as intersex.

The term manhood is used to describe the period in a human male's life after he has transitioned from boyhood, having passed through puberty, usually having attained male secondary sexual characteristics, and symbolises a male's coming of age. In English-speaking countries, many other words can also be used to mean an adult male such as guy, dude, buddy, bloke, fellow, chap and sometimes boy or lad.

The term manhood is associated with masculinity and virility, which refer to male qualities and male gender roles.

This is referred to as the XY sex-determination system and is typical of most mammals, but quite a few other sex-determination systems exist, including some that are non-genetic.

The term primary sexual characteristics denotes the kind of gamete the gonad produces: the ovary produces egg cells in the female, and the testis produces sperm cells in the male.

The concept of fatherhood and family exists in human societies.